diff --git a/v2rayN/v2rayN/Global.cs b/v2rayN/v2rayN/Global.cs
index 68bef5ae..3f1cd7a7 100644
--- a/v2rayN/v2rayN/Global.cs
+++ b/v2rayN/v2rayN/Global.cs
@@ -221,6 +221,10 @@ namespace v2rayN
         {
             get; set;
         }
+        public static System.Threading.Mutex mutexObj
+        {
+            get; set;
+        }
 
         #endregion
 
diff --git a/v2rayN/v2rayN/Program.cs b/v2rayN/v2rayN/Program.cs
index 13b666db..133e2108 100644
--- a/v2rayN/v2rayN/Program.cs
+++ b/v2rayN/v2rayN/Program.cs
@@ -1,6 +1,5 @@
 using System;
 using System.Diagnostics;
-using System.Reflection;
 using System.Threading;
 using System.Windows.Forms;
 using v2rayN.Forms;
@@ -32,9 +31,7 @@ namespace v2rayN
 
             //AppDomain.CurrentDomain.AssemblyResolve += CurrentDomain_AssemblyResolve;
 
-            Thread.Sleep(300); // 尽量避免切换语言后提示“已经运行”
-            Process instance = RunningInstance();
-            if (instance == null)
+            if (!IsDuplicateInstance())
             {
                 if (!UnzipLibs())
                 {
@@ -81,23 +78,17 @@ namespace v2rayN
         //}
 
         /// <summary> 
-        /// 获取正在运行的实例，没有运行的实例返回null; 
+        /// 检查是否已在运行
         /// </summary> 
-        public static Process RunningInstance()
+        public static bool IsDuplicateInstance()
         {
-            Process current = Process.GetCurrentProcess();
-            Process[] processes = Process.GetProcessesByName(current.ProcessName);
-            foreach (Process process in processes)
-            {
-                if (process.Id != current.Id)
-                {
-                    if (Assembly.GetExecutingAssembly().Location.Replace("/", "\\") == process.MainModule.FileName)
-                    {
-                        return process;
-                    }
-                }
-            }
-            return null;
+            //string name = "v2rayN";
+
+            string name = Utils.GetExePath(); // Allow different locations to run
+            name = name.Replace("\\", "/"); // https://stackoverflow.com/questions/20714120/could-not-find-a-part-of-the-path-error-while-creating-mutex
+            
+            Global.mutexObj = new Mutex(false, name, out bool bCreatedNew);
+            return !bCreatedNew;
         }
 
         static void Application_ThreadException(object sender, ThreadExceptionEventArgs e)