diff --git a/prompb/custom.go b/prompb/custom.go
index 0b3820c4d..4b07187bd 100644
--- a/prompb/custom.go
+++ b/prompb/custom.go
@@ -13,5 +13,22 @@
 
 package prompb
 
+import (
+	"sync"
+)
+
 func (m Sample) T() int64   { return m.Timestamp }
 func (m Sample) V() float64 { return m.Value }
+
+func (r *ChunkedReadResponse) PooledMarshal(p *sync.Pool) ([]byte, error) {
+	size := r.Size()
+	data, ok := p.Get().(*[]byte)
+	if ok && cap(*data) >= size {
+		n, err := r.MarshalToSizedBuffer((*data)[:size])
+		if err != nil {
+			return nil, err
+		}
+		return (*data)[:n], nil
+	}
+	return r.Marshal()
+}
diff --git a/storage/remote/codec.go b/storage/remote/codec.go
index 9b6f5a5ab..48c2d8615 100644
--- a/storage/remote/codec.go
+++ b/storage/remote/codec.go
@@ -20,6 +20,7 @@ import (
 	"net/http"
 	"sort"
 	"strings"
+	"sync"
 
 	"github.com/gogo/protobuf/proto"
 	"github.com/golang/snappy"
@@ -193,6 +194,7 @@ func StreamChunkedReadResponses(
 	ss storage.ChunkSeriesSet,
 	sortedExternalLabels []prompb.Label,
 	maxBytesInFrame int,
+	marshalPool *sync.Pool,
 ) (storage.Warnings, error) {
 	var (
 		chks []prompb.Chunk
@@ -234,12 +236,14 @@ func StreamChunkedReadResponses(
 				continue
 			}
 
-			b, err := proto.Marshal(&prompb.ChunkedReadResponse{
+			resp := &prompb.ChunkedReadResponse{
 				ChunkedSeries: []*prompb.ChunkedSeries{
 					{Labels: lbls, Chunks: chks},
 				},
 				QueryIndex: queryIndex,
-			})
+			}
+
+			b, err := resp.PooledMarshal(marshalPool)
 			if err != nil {
 				return ss.Warnings(), fmt.Errorf("marshal ChunkedReadResponse: %w", err)
 			}
@@ -247,6 +251,9 @@ func StreamChunkedReadResponses(
 			if _, err := stream.Write(b); err != nil {
 				return ss.Warnings(), fmt.Errorf("write to stream: %w", err)
 			}
+
+			// We immediately flush the Write() so it is safe to return to the pool.
+			marshalPool.Put(&b)
 			chks = chks[:0]
 		}
 		if err := iter.Err(); err != nil {
diff --git a/storage/remote/read_handler.go b/storage/remote/read_handler.go
index e1f1df21c..116eb9596 100644
--- a/storage/remote/read_handler.go
+++ b/storage/remote/read_handler.go
@@ -17,6 +17,7 @@ import (
 	"context"
 	"net/http"
 	"sort"
+	"sync"
 
 	"github.com/go-kit/log"
 	"github.com/go-kit/log/level"
@@ -37,6 +38,7 @@ type readHandler struct {
 	remoteReadMaxBytesInFrame int
 	remoteReadGate            *gate.Gate
 	queries                   prometheus.Gauge
+	marshalPool               *sync.Pool
 }
 
 // NewReadHandler creates a http.Handler that accepts remote read requests and
@@ -49,6 +51,7 @@ func NewReadHandler(logger log.Logger, r prometheus.Registerer, queryable storag
 		remoteReadSampleLimit:     remoteReadSampleLimit,
 		remoteReadGate:            gate.New(remoteReadConcurrencyLimit),
 		remoteReadMaxBytesInFrame: remoteReadMaxBytesInFrame,
+		marshalPool:               &sync.Pool{},
 
 		queries: prometheus.NewGauge(prometheus.GaugeOpts{
 			Namespace: "prometheus",
@@ -225,6 +228,7 @@ func (h *readHandler) remoteReadStreamedXORChunks(ctx context.Context, w http.Re
 				querier.Select(true, hints, filteredMatchers...),
 				sortedExternalLabels,
 				h.remoteReadMaxBytesInFrame,
+				h.marshalPool,
 			)
 			if err != nil {
 				return err
diff --git a/storage/remote/read_handler_test.go b/storage/remote/read_handler_test.go
index 03e4b706b..ba2517a40 100644
--- a/storage/remote/read_handler_test.go
+++ b/storage/remote/read_handler_test.go
@@ -107,6 +107,73 @@ func TestSampledReadEndpoint(t *testing.T) {
 	}, resp.Results[0])
 }
 
+func BenchmarkStreamReadEndpoint(b *testing.B) {
+	suite, err := promql.NewTest(b, `
+	load 1m
+		test_metric1{foo="bar1",baz="qux"} 0+100x119
+		test_metric1{foo="bar2",baz="qux"} 0+100x120
+		test_metric1{foo="bar3",baz="qux"} 0+100x240
+`)
+	require.NoError(b, err)
+
+	defer suite.Close()
+
+	require.NoError(b, suite.Run())
+
+	api := NewReadHandler(nil, nil, suite.Storage(), func() config.Config {
+		return config.Config{}
+	},
+		0, 1, 0,
+	)
+
+	matcher, err := labels.NewMatcher(labels.MatchEqual, "__name__", "test_metric1")
+	require.NoError(b, err)
+
+	query, err := ToQuery(0, 14400001, []*labels.Matcher{matcher}, &storage.SelectHints{
+		Step:  1,
+		Func:  "sum",
+		Start: 0,
+		End:   14400001,
+	})
+	require.NoError(b, err)
+
+	req := &prompb.ReadRequest{
+		Queries:               []*prompb.Query{query},
+		AcceptedResponseTypes: []prompb.ReadRequest_ResponseType{prompb.ReadRequest_STREAMED_XOR_CHUNKS},
+	}
+	data, err := proto.Marshal(req)
+	require.NoError(b, err)
+
+	b.ResetTimer()
+	b.ReportAllocs()
+
+	for i := 0; i < b.N; i++ {
+		compressed := snappy.Encode(nil, data)
+		request, err := http.NewRequest("POST", "", bytes.NewBuffer(compressed))
+		require.NoError(b, err)
+
+		recorder := httptest.NewRecorder()
+		api.ServeHTTP(recorder, request)
+
+		require.Equal(b, 2, recorder.Code/100)
+
+		var results []*prompb.ChunkedReadResponse
+		stream := NewChunkedReader(recorder.Result().Body, DefaultChunkedReadLimit, nil)
+
+		for {
+			res := &prompb.ChunkedReadResponse{}
+			err := stream.NextProto(res)
+			if err == io.EOF {
+				break
+			}
+			require.NoError(b, err)
+			results = append(results, res)
+		}
+
+		require.Equal(b, 6, len(results), "Expected 6 results.")
+	}
+}
+
 func TestStreamReadEndpoint(t *testing.T) {
 	// First with 120 samples. We expect 1 frame with 1 chunk.
 	// Second with 121 samples, We expect 1 frame with 2 chunks.