diff --git a/notifier/notifier.go b/notifier/notifier.go
index 218e4cb8c..5374e73d6 100644
--- a/notifier/notifier.go
+++ b/notifier/notifier.go
@@ -770,6 +770,7 @@ func (s *alertmanagerSet) sync(tgs []*targetgroup.Group) {
 
 	s.mtx.Lock()
 	defer s.mtx.Unlock()
+	previousAms := s.ams
 	// Set new Alertmanagers and deduplicate them along their unique URL.
 	s.ams = []alertmanager{}
 	s.droppedAms = []alertmanager{}
@@ -789,6 +790,17 @@ func (s *alertmanagerSet) sync(tgs []*targetgroup.Group) {
 		seen[us] = struct{}{}
 		s.ams = append(s.ams, am)
 	}
+	// Now remove counters for any removed Alertmanagers.
+	for _, am := range previousAms {
+		us := am.url().String()
+		if _, ok := seen[us]; ok {
+			continue
+		}
+		s.metrics.latency.DeleteLabelValues(us)
+		s.metrics.sent.DeleteLabelValues(us)
+		s.metrics.errors.DeleteLabelValues(us)
+		seen[us] = struct{}{}
+	}
 }
 
 func postPath(pre string, v config.AlertmanagerAPIVersion) string {